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CURRENT TRIALS
Hemorrhoids with Rectal Bleeding, and Pain or Itching
Hemorrhoids are caused by the enlargement of veins around the anus. This common condition most often causes painless rectal bleeding after bowel movements, characterized by bright red or ‘fresh’ bleeding on the stool, in the commode, or on the toilet paper. Pain and itching are additional symptoms caused by hemorrhoids.
This clinical trial is comparing the effectiveness of an ointment to a placebo that is applied into the anal canal two times daily for 14 days to stop hemorrhoid bleeding. The effect of the medication on pain and itching is also under study. Five scheduled visits include screening, 14-day treatment and 2-week follow-up. An extension of the study is available to individuals who qualify.
PRESENTLY ENROLLING!
Eligibility criteria include:
- Hemorrhoid bleeding for at least 2 consecutive days
- Pain or itching for at least 2 consecutive days
- Willingness to phone in daily responses to study medication
- Have had a colonoscopy in the past year if older than 40, or sigmoidoscopy if under 40
- Willingness to use an approved method of birth control (if required)
- Cannot have Irritable Bowel Syndrome, diarrhea, constipation, or prior hemorrhoid surgery
For further information please contact:
Sharon Debnam, R.N.
(336) 286-1194
email: sdebnam@vitalresearchnc.com
Treatment of Constipation-Predominant Irritable Bowel Syndrome (IBS-C)
This research study is designed to evaluate the safety and effectiveness of an investigational drug to relieve the symptoms of constipation-predominant Irritable Bowel Syndrome, such as constipation, bloating, and abdominal pain. The study medication will be taken orally once a day. The length of the study is 8 weeks.
The study requires four clinic visits that include physical exams and blood draws for laboratory studies. A colonoscopy is required within the last 5 years, after the onset of IBS symptoms. Participants will be asked to make entries into a telephone diary on a daily basis.
PRESENTLY ENROLLING!
Eligibility criteria include:
- 18-75 years of age
- Female and male
- Have less than 3 bowel movements per week
- Diagnosis of constipation-predominant Irritable Bowel Syndrome
- Willingness to record daily responses to study medication
- Have had a colonoscopy in the past 5 years
- Willingness to use an approved method of birth control (if required)
- Ability to discontinue medicines taken for constipation or that affect intestinal motility
For further information please contact:
Sharon Debnam, R.N.
(336) 286-1194
email: sdebnam@vitalresearchnc.com
Arthritis associated with Psoriasis (Psoriatic Arthritis)
Almost 40% of those with psoriasis may have complicating arthritis develop after the skin changes begin. Psoriatic Arthritis progresses over time causing destruction and deformity of the affected joints. This leads to disability and a higher risk of death. Because this is a chronic disease with limited treatment options, there is a need to develop more effective, better tolerated, and safer medications. This clinical research study will test a new investigational drug to see if it offers any of these advantages.
PRESENTLY ENROLLING!
Eligibility criteria include:
Psoriatic Arthritis diagnosed over 6 months duration Have 3 or more swollen AND 3 or more tender joints Male or female age 18 years or older Must be on stable dose of medicine(s) prior to and during the study Willing to use an approved method of birth control
For further information please contact:
Windy Crater
(336) 286-1194
email: wcrater@vitalresearchnc.com